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I usually tell people that the spine is part of the skeletal frame and when the spine is out of alignment, it changes the amount of stress on muscles, ligaments and tendons. It can even change the amount of pressure on internal organs. This stress left long enough will effect the entire body.

Also, the nervous system is encased in the spine and alterations in the spinal structure either directly or indirectly ( through swelling, inflamed muscles, etc)
can put pressure on the nerve system. The nervous system controls every cell, tissue, and organ in the entire body. This is why a subluxation of the spine can affect your overall health.

It can be a lot more complicated to explain all the mechanism of how the above happens; suffice it to say though, it is a good idea to make sure your spine is in alignment on a regular basis.